AM4 and AM5 are two generations of AMD’s desktop CPU sockets and are not mutually compatible.
AM4 is a mature, cost-effective platform based on DDR4 memory, while AM5 is the latest generation platform featuring DDR5 and PCIe 5.0 for higher performance and future upgradability.

Conclusion
In summary, AM4 remains an ideal choice for cost-sensitive and mainstream computing builds, while AM5 delivers superior performance, expandability, and long-term usability for users seeking a next‑generation computing platform.